On 16th of April, Ying Shang at Karolinska Institutet, defended her doctoral thesis entitled: “How can older adults combat diabetes to achieve a longer and healthier life?”.
The objective of the thesis was to investigate the impact of prediabetes and diabetes on health and survival among older adults, and to identify modifiable factors that may attenuate the risk of diabetes on disability and mortality to prolong survival with independence. Data used in this project were derived from the ongoing population-based Swedish National study on Aging and Care in Kungsholmen (SNAC-K). Overall, diabetes could increase the risk of dementia secondary to stroke and accelerate decline in physical function. This decline in physical function might start already during prediabetes. Yet, one out of five older adults with prediabetes could revert to normoglycemia with lifestyle modifications such as weight management. Diabetes is related to the risk of disability or death among older adults, but a healthy and socially active lifestyle may attenuate this risk and prolong disability-free survival.
Read more: Ying Shang, Thesis 2021
The NEAR researcher Johan Skoog, University of Gothenburg, defended his thesis with the title: “Sleep and cognition in old age: Birth cohort differences, dementia, and biomarkers of Alzheimer’s disease”.
The main findings from the thesis imply that 70-year old’s of today have better sleep quality, in terms of insomnia, than 70-year old’s 30 years ago (Do later-born birth cohorts of septuagenarians sleep better? Oxford Academic ). Different types of sleep problems may play varying roles during the life course concerning dementia risk; insomnia could potentially be more important in midlife while waking up too early (terminal insomnia) or long sleep duration (>9 hours) may be more critical later in life (Sleep disturbances and dementia risk: A multicenter study – ScienceDirect). This study included the NEAR databases: H70 and Kungsholmen Project, as well as the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study, which includes participants from Finland. Finally, sleep may play an important role in the early processes of Alzheimer’s Disease (AD) by potentially decreasing clearance or increasing production of amyloid β that is a biological marker for AD.
On 8 May Christina Dintica will defend her PhD thesis “Oral health and olfactory function: What can they tell us about cognitive aging?” in the Andreas Vesalius Hall, Berzelius väg 3, Karolinska Institutet, at 1:30 PM.
The thesis investigates the association between oral and olfactory conditions and cognitive trajectories, brain structural differences, and the risk of dementia.
Mozhu Ding belonged to the Aging research center, department of neurobiology, care sciences and society at Karolinska Institutet, Stockholm. Her Doctoral thesis “The Role of Atrial Fibrillation in Cognitive Aging: A population-based study” was defended on 12 December of 2019. Here, she gives a short presentation of her results.
The full text of the thesis, in English with summaries in Chinese and Swedish can be found via this link.
Stina Ek, PhD. Thesis title: “Predictors and consequences of injurious falls among older adults: a holistic approach”. Stina defended her thesis Oct 25, 2019 at Karolinska Institutet.
Johan Rehnberg, PhD. Thesis title: “Inequalities in life and death: income and mortality in an aging population”. Johan defended his thesis May 27, 2019 at Stockholm University.
Davide Liborio Vetrano, PhD, MD. Thesis title: “Impact of cardivascular and neuropsychiatric multimorbidity on older adults’ health”. Davide defended his thesis May 13, 2019 at Karolinska Institutet.
Kuan-Yu Pan, PhD. Thesis title: “Impact of psychosocial working conditions on health in older age”. Kuan-Yu defended his thesis June 5, 2019 at Karolinska Institutet.
Malin Ericsson from the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, defended her thesis “Socioeconomic influences on late-life health and mortality: Exploring genetic and environmental interplay” on 4 October, 2019.
The full thesis, with summary in English and Swedish can be found via this link.