Ongoing projects

All NEAR projects are based on at least two or more databases within NEAR. Below is a list of the ongoing projects.

1. Physical function before death – Linda Enroth, University of Tampere, Finland
2. Medications’ effects on trajectories of biological age – Sara Hägg, Karolinska Institutet 
3. Simul-Age – Björn Slaug, Lund University
4. The effect of exclusion from social relations – Andreas Motel-Klingebiel and George Pavlidis, Linköping University
5. A metric for global brain integrity  – Lars Nyberg, Umeå University
6. Cohort differences in dementia risk factors – Scott Hofer, VA Pacific Islands Health Care System and Pacific Health Research and Education Institute.
7. Sleep disturbances and MRI – Shireen Sindi, Karolinska Institutet
8. Birth cohort differences in the body mass index (BMI)-mortality association – Anna Dahl Aslan, University of Skövde
9. Stress and cognitive and physical function – Ingemar Kåreholt, Jönköping University
10. Aging frailty and cardiovascular risk – Francesca Leva, University of Milan
11. Green brain: Investigating the role of green-blue space for neurocognitive status – Cecilia Stenfors
12. Sex-specific differences, inflammation, late-life depression – Ingmar Skoog, University of Gothenburg
13. Role of physical health conditions for terminal decline in well-being – Denis Gerstorf, Humboldt University of Berlin 
14. Sleep, cognition and pain – Anders Behrens, Blekinge Institute of Technology
15. Care in people with dementia – Weili Xu, Karolinska Institutet
16. Trajectories of care needs – Davide Vetrano, Karolinska Institutet
17. Smell and depression – Ingrid Ekström, Karolinska Institutet
18. Personality traits and biomarkers of cognitive disorders – Robert Sigström, University of Gothenburg
19. Body mass index (BMI) and frailty index – Alessandra Marengoni, Brescia University
20. Herpes and cognitive decline – Pascal Geldsetzer, Stanford University
21. Intergenerational differences in cognitive trajectories: role of cardiovascular health and cognitive reserve – Giulia Grande, Karolinska Institutet  
22. Nutritional status among very old adults in urban and rural areas in Sweden – Birgitta Olofsson, Umeå University
23. Dietary patterns and malnutrition in older adults: a multicohort study – Adrián Carballo Casla, Karolinska Institutet
24. Validation of the Health Assessment Tool (HAT) in the Swedish National Study on Aging (SNAC), Part II, Amaia Calderón-Larrañaga, Karolinska Institutet
25. Old-age depression: Temporal and regional differences and their implications for treatment and healthcare utilization patterns in old age – Serhiy Dekhtyar, Karolinska Institutet
26. Low and Declining Risk-factors preceding Dementia (LODERID) study – Jan Willem van Dalen, Radboud University Medical Center
27. Validation of dementia diagnosis – Debora Rizzuto, Karolinska Institute
28. Identifying Falls Risk Factors in Older Adults with Cognitive Impairment: Toward Targeted Prevention Strategies – Anna-Karin Welmer, Karolinska Institutet
29. An investigation into the use of Swedish snus and its association with cognition and dementia – Manasa Shanta Näsholm, Karolinska Institutet
30. Female-specific factors, biological and neuroimaging correlates, and the risk of dementia – Jessica Gong, University College London
31. Development of Predictive Models for Dementia and COPD Using AI and Longitudinal Data – Ana Luiza Dallora Moraes, Blekinge Tekniska Högskola
32. Transforming Care for Older Adults with Cardiometabolic and Cognitive Multimorbidity: Person-Centered, Integrated, and Action-Oriented Approaches for Real-World Complexity – Weili Xu, Karolinska Institutet
33. Sex disparities in social health, resilience, and cognition across the life course: the interplay between biological and sociocultural aspects – Anna Marseglia, Karolinska Institutet
34. Artificial intelligence (AI) and dementia – Ashir Javeed, Blekinge Institute of Technology
35. Diabetes and cognitive trajectories – Francesca Remelli, Università degli studi di Ferrara
36. Sleep Health of Older Adults in Home Care – Sandra Öberg, Jönköping University
37. Evaluating Missing data imputation methods with application to disease risk prediction – Rani Basna, Lund University
38. Appetite Loss and Its Association with Dietary Intake, Nutrient Status, and Functional Outcomes in Older Adults – Annelie Turesson, Uppsala University
39. Transportability of missing data models across study sites for research synthesis – Robert Thiesmeier, Karolinska Institutet
40. Robust Imputation of Missing Lactate Measurements in Cardiogenic Shock Research – Robert Thiesmeier, Karolinska Institutet
41. Intermittent Observation and Time‑to‑Event Analyses in Aging and Epidemiological Research – Caterina Gregorio, Karolinska Institutet
42. Hidden multistate models to study multimorbidity trajectories – Caterina Gregorio, Karolinska Institutet
43. STREAMS: Semi-supervised Trajectory Reconstruction Across Interval Censored Multi-State Models – Caterina Gregorio, Karolinska Institutet
44. Methods for Single and Multilayer Network Analysis for Biomedical Research: The MixMashNet R package – Caterina Gregorio, Karolinska Institutet
45. Quality of Life Among Older Adults Participating in Organized Exercise – Mattias Forsblad, Linköping University
46. Error pattern analysis to enhance the predictive power of olfactory and cognitive tests – Jonas Olofsson, Stockholm University
47. Interplay between allostatic load and sleep in brain aging: separate and interactive associations – Jasper Holleman, Karolinska Institutet
48. To explore how genetic factors for education and childhood socioeconomic environment influence late-life cognitive abilities, and whether this varies by birth cohorts and sex – Malin Ericsson, Karolinska Institutet
49. Using the cotwin control design to eliminate genetic confounding, we will test occupational characteristics – Brian Finch, University of Southern California
50. Do socioemotional factors and physical activity modify associations Between Hand Grip Strength and Alzheimer’s Disease and Related Dementias outcomes across mid to late life? – Tara Henechowicz, University of Colorado Boulder
51. Investigate the association between dementia risk and change in BMI from mid- to late-life – Yuling Yu, Karolinska Institutet
52. Depression occurrence in late life and its correlates in Sweden – Federico Triolo, Karolinska Institutet
53. Validating and Refining Dementia Risk Prediction Models in Population-Level and Disease-Specific Cohorts – Stephan Blossom, Curtin University
54. Beyond the plate: novel techniques and exposure dimensions in geriatric nutritional epidemiology – Adrián Carballo Casla, Karolinska Institutet
55. Multimodal Interpretable Transformer for AD (MINT-AD) & Agentic Harmonization Assistant (aha) – Carlos Eduardo Ramírez, IGC Pharma (India Globalization Capital, Inc.)
56. Constructing a data-driven dietary pattern for dementia – Anja Mrhar, Karolinska Institutet
57. Where you live, how you age: How neighborhood socioeconomic conditions shape dementia risk in Sweden – Abigail Dove, Karolinska Institutet