Debora Rizzuto opening the NEAR Workshop on Zoom.

NEAR’s second scientific workshop was conducted remotely over Zoom with 82 connected participants. It was chaired by Debora Rizzuto.

After a short update and welcome address by Laura Fratiglioni, Johan Skoog from the University of Gothenburg presented the NEAR sleep disturbance and cognition project, an ongoing cooperation between researchers in the H70, KP&SNAC-K, GÅS/SNAC-S, CAIDE studies and the NEAR operational group. Both insomnia in midlife and long sleep duration has been shown to be associated with higher risk for dementia, and sleep disturbances are also associated with lower MMSE scores. Multi-level models are applied but more work is needed to harmonize the differing variable measurements between the studies.

Linda Enroth from Tampere University, Finland, presented the outline of a project she is setting up, using NEAR data from nine studies. The general aim of the project is to examine the health consequences of the increasing life expectancy by analyzing disability rates and trajectories during the last years of life. It further seeks to investigate the role of sex and socioeconomic inequality behind these traits.

Enrico Ripamonti, NEAR statistician, gave a presentation on ongoing collaborative work regarding lifetime determinants of the cognitive status in older age. The work employs several waves from six databases from SOFI, NEAR and Finnish studies, including life-level analyses of younger age cohorts with outcomes at high age (>75 years).

The NEAR platform for database access and analysis will be launched during the autumn. Xiaonan Hu, NEAR data scientist, ended the workshop by demonstrating its functionality and showing examples from the SNAC-K study, which is already accessible.

The presentations rendered many follow-up questions and positive comments and will likely lead to future cooperations.

We are happy to announce that NEAR will hold its second workshop 23d of September online. You are more than welcome to participate!

Link to Zoom meeting: https://ki-se.zoom.us/j/62280692747

 

Welcome to the second NEAR Workshop, at 13–15

Chair:Debora Rizzuto, NEAR Scientific Coordinator, Assistant professor in epidemiology

 

13:00–13:15 Welcome and update
Laura Fratiglioni, Professor at KI, PI for SNAC-K & KP, and Director of NEAR

 

Presentations:

13:15–13:35 Sleep disturbances and cognitive decline
Johan Skoog, PhD Student, Gothenburg University.

 13:35–13:55 Physical function before death
Linda Enroth, PhD, Tampere University.

BREAK

14:10–14:30 Lifecourse determinants of health status among elderly
Enrico Ripamonti, PhD, NEAR Statistician

 

14:30–14:45 Launch/demonstration of the NEAR Platform
Xiaonan Hu, PhD, NEAR Data Scientist

 

Download programme

IAGGER              

NEAR was well-represented during the International Association of Gerontology and Geriatrics European Region (IAGG-ER) Congress 2019 in Gothenburg.

The NEAR director Laura Fratiglioni had a key stage talk with the title: “NEAR: A common effort for a better future” where she talked about how solutions for a better life in old age can be found in Swedish research.

 

NEAR also held a well-visited symposium with the title: “NEAR – the National E-infrastructure on Aging Research in Sweden: Building on 30 Years of Experience to Prepare for Future Aging Research”

Chair: Laura Fratiglioni, Karolinska Institutet and Stockholm University, Co-chair: Debora Rizzuto, Karolinska Institutet and Stockholm University.

  1. Social Inequalities in old age. Speaker: Carin Lennartsson, Karolinska Institutet and Stockholm University.
  2. Care of elderly people. Speaker: Anders Wimo, Karolinska Institutet.
  3. Gene-Environmental Interplay to Explain Health Heterogeneity: Results from the Swedish Twin Registry. Speaker: Nancy Pedersen, Karolinska Institutet
  4. Redefine dementia diagnosis etiology in epidemiological studies. Speaker: Ingmar Skoog, University of Gothenburg.

         

Many persons also came to visit our booth where information about NEAR and NEAR-related activities could be found.

 

NEAR would like to thank the organizers for hosting a fantastic and stimulating congress and we are looking forward to upcoming IAGG-ER conferences!

IAGGER              

We are happy to announce that NEAR will host its first symposium with the title: “NEAR – the National E-infrastructure on Aging Research in Sweden: Building on 30 Years of Experience to Prepare for Future Aging Research” at the International Association of Gerontology and Geriatrics European Region Congress, May 2019 in Gothenburg, Sweden (IAGG-ER 2019).

We hope to see you there!

 

SYMPOSIUM PROGRAM

NEAR – the National Infrastructure on Aging Research in Sweden: building on 30 years of experience to prepare for future aging research

Chair: Laura Fratiglioni, Karolinska Institutet and Stockholm University, Co-chair: Debora Rizzuto, Karolinska Institutet and Stockholm University.

  1. Gene-Environmental Interplay to Explain Health Heterogeneity: Results from Swedish Twin Register. Speaker: Nancy Pedersen, Karolinska Institutet
  2. Social Inequalities in Health in old age. Speaker: Johan Fritzell, Karolinska Institutet and Stockholm University.
  3. Redefine dementia diagnosis etiology in epidemiological studies. Speaker: Ingmar Skoog, University of Gothenburg.
  4. Care of elderly people. Speaker: Anders Wimo, Karolinska Institutet.
  5. Neuroimaging Biomarkers in Brain Ageing. Speaker: Lars Nyberg, Umeå University.

 

Abstract

Since the 1970s, Swedish longitudinal population-based studies have played a major role in geriatric research by exploring health-related conditions in older adults. Most of those studies are now collaborating to build the newly started National E-infrastructure for Aging Research (NEAR) to empower aging research in Sweden. This symposium presents and discusses some of the breakthrough contributions of the participating studies. The Gothenburg Population Studies will provide a comprehensive overview of the role vascular factors play in dementia and Alzheimer disease, starting with pioneering evidence of the impact of high blood pressure on dementia risk. Findings from the Swedish Twin Registry, which uses a life course approach, will also be presented. This research has quantified genetic and environmental influences on common chronic disorders and individual changes in physical and cognitive functioning. SWEOLD will present results on the relevance of living conditions and family connections to well-being and healthy aging, as well as information on health inequality by sex, education, and socioeconomic position found in older adults, even in Sweden. Speakers will also cover findings on the complexity and heterogeneity of older adults’ health in relation to care needs and use of medical and social resources, based on integrated information from the four SNAC studies. For a more complete picture, temporal trends of different health indicators will also be presented. Finally, findings from the Betula project will be presented; researchers have observed large heterogeneity in memory-aging profiles linked not only to genetic and lifestyle-related factors but also to specific brain characteristics that could be used as clinically relevant biomarkers. In conclusion, NEAR integrates rich medical and social data and brings together the scientific experience of its founders, providing unique opportunities to identify sustainable intervention strategies for better health and care for old people.

NEAR’S FIRST SCIENTIFIC WORKSHOP

On March 7th to March 8th, the National E-Infrastructure on Aging Research (NEAR) hosted its first internal scientific workshop to initiate discussions for potential future research collaborations. On behalf of Karolinska Institutet, the Vice President of Research, Anders Gustafsson, welcomed everyone and enlightened the importance of epidemiological aging research, as well as the added value of national collaborations across the largest Swedish Universities in the medical field. The workshop continued with that the Director of NEAR, Laura Fratiglioni, and the Scientific Coordinator, Debora Rizzuto, had presentations about NEAR. This was followed by speakers with experience of research collaborations across various databases/studies.

In the afternoon brainstorming sessions took place to facilitate discussions of future research collaborations. On Friday the workshop ended with presentations and discussions of the future research projects and collaborations. Overall, the workshop was very successful, resulting in interesting and important research- and methodological related discussions, new ideas, as well as proposals of 10 future research studies.

For detailed program: NEAR Program_Workshop_7 to 8 March_2019 _Final